Procalcitonin as a Marker of Bacterial Sepsis: Time for a Reappraisal?

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection.1 It frequently leading death from septic shock and multi failure worldwide. can be any infection, either fungal, viral, parasitic, or bacterial, not all of these pathogens cultured. In around half patients with sepsis, no pathogen identified.2 For every hour delayed treatment the risk mortality sepsis increases 4-9%.3 takes 11 million lives world each year, contributing 20% deaths globally taking more than cancer.4 There 20 minute.5 Before onset dysfunction, infections should identified this requires rapid diagnosis prompt initiation treatment. J Bangladesh Coll Phys Surg 2023; 41:183-184